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Table 4 Organ weights of adult F2. All the data were expressed as % of body weight (mean ± SEM). *p < 0.05 versus FA, one-way ANOVA. M/F2, F2 offspring in the maternal line; P/F2, F2 offspring in the paternal line

From: Developmental programming of obesity by maternal exposure to concentrated ambient PM2.5 is maternally transmitted into the third generation in a mouse model

  M/F2 P/F2
Male Female Male Female
FA CAP FA CAP FA CAP FA CAP
Perigonadal fat 1.14 ± 0.02 1.80 ± 0.25* 1.09 ± 0.11 1.30 ± 0.14 0.99 ± 0.14 1.14 ± 0.27 1.08 ± 0.30 1.34 ± 0.17
Perirenal fat 0.45 ± 0.01 0.79 ± 0.18* 0.41 ± 0.04 0.49 ± 0.03 0.37 ± 0.06 0.49 ± 0.06 0.55 ± 0.17 0.45 ± 0.03
Subcutaneous fat 0.57 ± 0.00 0.71 ± 0.07 0.78 ± 0.06 0.79 ± 0.04 0.46 ± 0.03 0.61 ± 0.02 1.00 ± 0.19 0.83 ± 0.04
Brown fat 0.31 ± 0.00 0.37 ± 0.05 0.27 ± 0.00 0.35 ± 0.02 0.27 ± 0.06 0.32 ± 0.00 0.25 ± 0.03 0.30 ± 0.02
Kidney 1.36 ± 0.01 1.32 ± 0.01 1.36 ± 0.03 1.55 ± 0.03 1.38 ± 0.00 1.32 ± 0.01 1.29 ± 0.16 1.48 ± 0.02
Pancreas 0.64 ± 0.01 0.58 ± 0.03 0.61 ± 0.02 0.79 ± 0.03 0.65 ± 0.05 0.71 ± 0.02 0.80 ± 0.05 0.75 ± 0.05
Liver 5.19 ± 0.05 4.84 ± 0.31 5.69 ± 0.16 6.46 ± 0.21 5.50 ± 0.12 5.09 ± 0.02 4.88 ± 0.32 5.24 ± 0.21
Heart 0.54 ± 0.00 0.51 ± 0.02 0.53 ± 0.01 0.58 ± 0.02 0.56 ± 0.00 0.54 ± 0.00 0.55 ± 0.06 0.62 ± 0.02
Lung 0.76 ± 0.01 0.68 ± 0.00 0.81 ± 0.01 0.89 ± 0.00 0.83 ± 0.02 0.73 ± 0.01 0.87 ± 0.02 0.82 ± 0.03
Spleen 0.52 ± 0.03 0.41 ± 0.00 0.42 ± 0.02 0.54 ± 0.03 0.46 ± 0.02 0.36 ± 0.00 0.64 ± 0.02 0.58 ± 0.09
Testis/Ovary 0.79 ± 0.01 0.68 ± 0.02 0.03 ± 0.00 0.04 ± 0.00 0.73 ± 0.00 0.66 ± 0.01 0.02 ± 0.00 0.03 ± 0.00
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Particle and Fibre Toxicology

ISSN: 1743-8977

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